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Sandu C, Dumas M, Malan A, Sambakhe D, Marteau C, Nizard C, Schnebert S, Perrier E, Challet E, Pevet P, Felder-Schmittbuhl MP (2012) Human skin keratinocytes, melanocytes, and fibroblasts contain distinct circadian clock machineries
Also, after weight loss surgery, patients are on a very restricted diet and adjusting to a reduction in stomach capacity making it difficult to ingest all the nutritional supplements required
The 100mg daily dose provides maximum NNMT inhibition while remaining within established safety parameters