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lyophilization removes moisture to inhibit this Light: UV radiation can cause oxidative damage to aromatic and sulfur-containing residues Freeze-thaw cycling: Ice crystal formation during freezing can physically disrupt peptide structure

Wespes et al

doi: 10.1038/s41581-022-00633-5 2 PradeuTThommaBGirardinSELemaitreB

Lets debunk the myths about this natural bodily compound, which has been garnering attention lately

Chemically it is not a peptide at all, so the peptide dosing mental model only partly applies: the reconstitution math is identical, but the route options are broader (a small molecule can survive and be studied by mouth in a way most peptides cannot)