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They play a key role in: Allergic reactions Wound healing Immune defense against pathogens Regulating inflammation When activated, mast cells release granules filled with bioactive substances, including: Histamine Tryptase Prostaglandins Leukotrienes Cytokines This process is called degranulation and in normal situations (e.g., in response to an insect sting or parasite), it's protective

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All trials employed randomized, double-blind, placebo-controlled designs, representing the gold standard for clinical research

It may almost look unreal, but for some, there may be no difference at all