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Psychiatry 87 , 144148 (2016)
When you discontinue semaglutide (marketed as Ozempic and Rybelsus for type 2 diabetes and Wegovy for chronic weight management), the medication's effects on your body gradually diminish over several weeks
This disrupts the function of L-cells, reducing the release of GLP-1 and leading to poor glucose metabolism
Slowing gastric emptying: Mounjaro slows down the movement of food from the stomach into the small intestine, which helps you feel full for longer and eat less
7,8,9 The 2024 Dao study of 168 first-trimester GLP-1 exposures and the 2024 Cesta study of 938 periconceptional GLP-1 exposures both found no significant increase in major birth defects
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