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[1] Systematic reviews and meta-analyses of randomized controlled trials report that retatrutide produces substantial reductions in body weight in adults with obesity, with mean percentage weight loss typically between 15 and 24 percent over 48 to 72 weeks, depending on study protocols and populations

Most athletes tolerate it extremely well

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This article reviews the current data on tirzepatide and sexual function, explores alternative explanations for ED symptoms during treatment, and provides guidance on when to seek medical evaluation for erectile difficulties