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Image credit: Yusia13/Shutterstock.com In a recent study published in eBioMedicine , researchers report that tirzepatide, a dual incretin agonist targeting receptors for glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), may represent a potential therapeutic avenue for treating alcohol use disorder (AUD)
Drinking enough water can improve focus and energy levels without needing to adjust medication
Copper peptides are generally not recommended during pregnancy or breastfeeding due to insufficient research, not known harm
However, if you also take insulin or sulfonylureas, NICE recommends regular testing (typically before meals and at bedtime) due to increased hypoglycaemia risk, particularly during dose titration
Orthostatic considerations Orthostatic hypotension (a drop of 20 mmHg systolic or 10 mmHg diastolic on standing) can develop during early treatment for several reasons: Reduced fluid intake from nausea Reduced sodium intake from decreased eating Continued full-dose antihypertensive medications as BP drops Volume contraction from weight loss Patients should be counseled to rise slowly, maintain hydration, and contact their clinician if they experience dizziness on standing
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