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Semaglutide carries warnings about potential thyroid tumors based on rodent studies, though this has not been demonstrated in humans
Among participants without diabetes, cardiovascular risk reduction was consistent across all baseline HbA1c subgroups (less than 5.7%, 5.7% to 6.0%, and 6.0% to 6.5%) and across categories of HbA1c change from baseline to 20 weeks
In GLP-1 receptor agonist trials, headache occurred in approximately 10-25% of participants, making it one of the more commonly reported neurological adverse events alongside nausea and dizziness
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