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Clinical experience with therapeutic FAP-targeted radioligand therapy using Lu-177-FAPI-2286 in advanced sarcoma

Glioma cells with FAO inhibited by etomoxir, a CPT1 inhibitor, exhibits a profound decrease in NADPH levels, reduced GSH content and elevation of intracellular ROS levels

Compared to traditional single-target anti-inflammatory strategies, this approach improves the efficiency of inhibiting renal fibrosis in the chronic phase of IRI by 41%, demonstrating the long-term advantages of immune network regulation

Calcium-independent phospholipase A2 (iPLA2), a member of the PLA2 family, is a cytoplasmic protein with catalytic activity in the absence of calcium, and previous studies have shown that it is associated with metabolic disorders and inflammation [40]

Furthermore, glutathione is often fragile