If your doctor supports you trying a supplement, look for one thats third-party certified, which ensures that the product is labeled accurately and is free of contaminants
If someone's diet is low in fiber (as most Western diets are), adding a concentrated fiber supplement will likely produce some positive effects on appetite and digestive comfort
Care should be taken when combining topiramate with other antiepileptic drugs, other carbonic anhydrase inhibitors, CNS depressants, estrogen-containing or progestin-only contraceptives, hydrochlorothiazide (HCTZ), diabetes drugs, lithium, amitriptyline, antihistamines, or alcohol
DOI Malmlf K, Johansen PB, Haahr PM, Wilken M, Oxlund H (1999)
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