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Recommend switching to a non-oral contraceptive or adding a barrier method for 4 weeks after starting or increasing the dose

When administered to juvenile rats, melanotan II elicits positive effects on the hypothalamic neurocircuitry system, as well as the homeostatic conditions of body weight, NPY expressions, and energy expenditure

Combining mono- and/or dual-agonists to achieve triple agonism may allow for personalisation of treatment, aiming to find the optimal balance of receptor agonism for a specific individual

Insulin resistance can lead to weight gain, which can make PCOS symptoms worse

GLP-1s and Chronic Therapy If you stop taking GLP-1s, there's a chance you'll gain back some weight