GLP-1, a hormone primarily secreted from the ileum in response to nutrient intake, exerts multiple metabolic effects including appetite suppression, delayed gastric emptying, enhanced insulin secretion, and inhibition of glucagon release [4]
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Ammonium also promotes tumor immune escape by modulating immune regulatory pathways
Novo, which was the first to bring GLP-1s to market, has been outpaced in sales by Lilly this year