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It is synthesized as a proreceptor that is cleaved into alpha and beta chains and assembled into a covalent heterotetramer, two alpha subunits and two beta subunits held together by disulfide bonds, which sits in the membrane as a preformed dimer even in the absence of ligand
Sleep and circadian rhythms in humans
Endocrinology 151: 1984-1989, 2010
To induce OA, the rabbits were first anesthetized using a combination of xylazine and ketamine
Specifically, more eumelanin the dark brown pigment responsible for a deep, even tan
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