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Description

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A portion of the kidney, weighing about 100 mg, was cut in cross-section and stored in RNAlater for gene expression analysis

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Regenerative and protective actions of the GHK-Cu peptide

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While it inhibits fibrosis by activating the Keap1-Nrf2 pathway and downregulating the phosphorylation of Smad3 and STAT3, the interactions among involved signaling pathways (such as PI3K/Akt, MAPK, TGF-, Wnt/-catenin) and their roles at different pathological stages have not been systematically studied

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