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14Mischley LK, Allen J, Bradley R

As a highly conserved proto-oncogene-encoded protein, c-Myc acts as a master regulator of cell cycle progression, proliferation, and metabolic reprogramming [39,40,41]

Because human safety data are still limited and BPC-157 is not FDA-approved, patient selection matters

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It is hypothesized that this results in a glutamate surge, ultimately agonizing postsynaptic AMPA-glutamate receptors and triggering production of brain-derived neurotrophic factor, which orchestrates synaptogenesis and neuroplasticity ( This cascade of events is believed to be responsible for the observed increase in global brain connectivity in the prefrontal cortex of individuals with MDD within 24 hours of a single ketamine infusion and imaged with functional connectivity MRI