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As of February 2026, it remains in Phase 3 clinical trials

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The oral route of drug delivery is challenging for peptides because the GI tract is specifically designed to break down proteins and peptides into their constituent amino acids for absorption

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JAMA Internal Medicine (2016): In over 1.5 million patients, incretin-based drugs, including GLP-1s, had an adjusted hazard ratio of 1.04 (95% CI, 0.811.35) for acute pancreatitis

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