Janosik M, Kery V, Gaustadnes M, Maclean KMN, Kraus JP: Regulation of human cystathionine beta-synthase by S-adenosyl-L-methionine: Evidence for two catalytically active conformations involving an autoinhibitory domain in the C-terminal region
Over multiple cycles, this contributes to: Physical aggregation (clumping) of peptide molecules Potential denaturation of three-dimensional structure Gradual loss of biological activity in research assays The practical solution is simple: aliquot before freezing
Our results strongly suggest that although not universal, ZIL and ZIL aq
Vargas DL, Nascimbene C, Krishnan C, Zimmerman AW, Pardo CA
Quellen Pickart L, Margolina A (2018)