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GLP-1 weight-loss drugs are no longer a healthcare side story
This can help to encourage you to eat less
This is expected with any GLP-1 receptor agonist because slowing gastric emptying and suppressing appetite inevitably affects digestive function
Interestingly, the SURMOUNT-5 trial found that gastrointestinal adverse events causing treatment discontinuation occurred in 5.6% of semaglutide users compared to only 2.7% of tirzepatide users
Additionally, it is suggested that the beneficial effects of GLP-1RAs on systolic blood pressure may be due to improvements in direct or indirect vasorelaxation of vascular smooth muscle in the kidneys as well as via endothelial function and natriuresis [98]
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