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The clinical appearance is one of the brown to black spots or macules, with a histopathological increase in melanin in the basal cell layer of the oral epithelium and melanin incontinence in the upper portion of the lamina propria, but without an increase in the number of melanocytes [11, 39, 40]
J Lipid Res 19:924928 US F.a.D.A
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M.AdnanM.AlamS.HassanM
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