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The primary endpoint was a change in hepatic steatosis by nuclear magnetic resonance spectroscopy (NMRS)

In vitro drug screens are performed on either cell-free protein aggregates, animal-derived cell lines, or patient-derived motor neurons [7, 197]

Pre-treatment with topical anesthesia may be required as well

Gross-total resection (GTR) was the treatment of choice in all amenable cases, followed in selected cases with residual tumor by adjuvant radiotherapy or chemotherapy