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These medications were prescribed for, among other things, the treatment of Type 2 diabetes and more recently, for weight loss
doi: 10.3390/nu10111564 72 MasamhaCPLaFontaineP
This is a plausible pharmacological concern but has not been demonstrated in any human trial comparing the two forms directly
c , Protein levels from cancer cell lines from DepMaps CCLE (Proteomics GGT1: P19440 (n = 339), GGT5: P36269 (n = 108), GGT6: Q6P531 (n = 45), GGT7: Q9UJ14 (n = 375))
59,60 Specific genes implicated include vascular endothelial growth factor (VEGF), neurotrophic receptor tyrosine kinase 1, sodium voltage-gated channel alpha subunit 2 (SCN2A), angiotensin-converting enzyme, and methylenetetrahydrofolate reductase, with polymorphisms associated with increased DN susceptibility
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