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AOAC, Official Methods of Analysis

IGF-DES Potency vs Native IGF-1 Studies using cultured cells confirmed that the biological potencies of IGF-1, IGF-2, and des-(1-3)-IGF-1 correlate inversely with their binding to IGFBP proteins in conditioned media establishing that des-(1-3)-IGF-1s enhanced in vivo and in vitro potency is a direct consequence of reduced IGFBP sequestration rather than greater intrinsic receptor affinity

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PD1 are mainly converted by DHA and have anti-inflammatory, neuroprotective, and anti-apoptotic (anti-cell death) properties (62), Core functions: (1) Minimize oxidative stress and safeguard cells against harm, (2) reduce apoptosis, especially in nerve cells, protect hippocampal neurons from status epilepticus damage

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