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FIGURE 4 GSTP1 Activity in GSH-Conjugation of AQ-QI and DEAQ-QI To investigate the intracellular GSTP1-mediated GSH-conjugation of AQ-QI or DEAQ-QI, AQ-SG, and DEAQ-SG formation were measured in total lysates directly after QI exposure

However, due to their systemic toxicity, low drug loading efficiency, and nonspecific targeting for tumor cells, anti-tumor efficacy is not ideal

Supplements such as N-acetylcysteine moreover alpha-lipoic acid also help raise glutathione levels when the body faces more harmful effects from oxygen

Solvent : Use deoxygenated solvents for reconstitution

Fructose inhibits apoptosis induced by reoxygenation in rat hepatocytes by decreasing reactive oxygen species via stabilization of the glutathione pool