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A team of students at Trinity College, University of Cambridge, has investigated the impact of stopping the medication, modelling the trajectory of weight regain over 12 months and beyond

Collectively, these studies indicate that the antihypertensive effect of GLP-1 is mediated by its natriuretic effect on the kidneys, vasodilation on endothelial cells, and reduction of sympathetic activity on brain stem catecholamine neurons (95)

Methods Animals Adult male Sprague-Dawley rats (Charles River Laboratories, USA) were individually housed in double-wide cages with a temperature and humidity-controlled environment on a 12-hour/12-hour light-dark cycle

With that weight loss comes lower cholesterol levels and improved blood pressure and blood sugar, all contributing to lower cardiovascular risk

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