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But then there was a new paper in Nature Medicine in 2018 that started to focus in on neuroinflammation

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It may be promising, but it is not yet proven.

We also manually searched the websites of the EASD and ADA scientific meetings, and ClinicalTrials.gov to retrieve either additional eligible trials or any additional information for trials already identified through the database searches

Contraindications, Cautions and Common Mistakes Standard injectable contraindications apply: pregnancy and breastfeeding, active infection at the treatment site, known allergy to any disclosed ingredient, and caution around anticoagulant use given the bruising risk