Growth-stimulatory actions of insulin in vitro and in vivo
The authors hypothesized that early life adversity may alter oral microbiome composition, which can shift to gut via saliva, potentially creating a pro-inflammatory state that increases vulnerability to PTSD following subsequent trauma exposure (Malan-Muller et al., 2022)
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Indeed, both mRNA and protein levels were reduced in keratinocytes retrotransduced with the high-risk HPV16E6 compared to the control (Scalise et al., 2012)