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You may see products slamming terms like green tea extract, raspberry ketones, garcinia cambogia, and similar ingredients that have no meaningful clinical evidence for weight loss
In this combined analysis, we observe that the degree of BMI loss depends strongly on sex, drug type, time on treatment and drug dosage, consistent with previous reports 11 , and has a relatively weak dependence on pre-treatment BMI (with higher starting BMI associated with greater BMI loss)
The largest of these (still fairly small, n=159) was a randomized and controlled clinical trial published in the New England Journal of Medicine , and found that a dose of 100 mcg twice per day improved quality of life, reduced eye involvement, and slowed disease progression among participants with mild Graves' orbitopathy (compared to pentoxifylline or placebo)
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Body composition analyses using dual-energy X-ray absorptiometry (DEXA) scans revealed that a majority of the weight lost was fat mass
