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It works through biological modulation of melanin synthesis a process that follows the skins natural cellular renewal cycle (approximately 2840 days in adults)

5A-1MQ-treated mice switched from WD to LD (WD/LD-T) showed a rather reduced relative abundance of Akkermansia compared to vehicle-treated DIO animals switched from WD to LD (WD/LD-V), suggesting a unique microbiome mechanism associated with weight loss in the vehicle-treated group switched from WD to LD compared to the 5A-1MQ-treated group that underwent the same diet switch

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For each transcript, the table reports the log 2 -transformed average gProcessed signal from three biological replicates, the fold change between the various experimental groups expressed as log 2 ratio (LPS vs control and BSO/LPS vs LPS) and the respective P -value for each comparison, obtained by two-tailed Students t -test