In summary, incretins serve as integral contributors to glucose metabolism by promoting insulin release, inhibiting glucagon secretion, supporting beta cell function and survival, and mitigating appetite and food consumption
Hypoglycemia risk, while generally low with tirzepatide monotherapy, increases in patients taking concurrent diabetes medications, particularly insulin or sulfonylureas
If symptoms persist beyond three weeks or become severe, your provider may recommend a temporary dose adjustment, switching to oral tirzepatide, or exploring alternative PlexusDx formulations such as semaglutide-only or GLP-Squared compounds
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