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A systematic review indicated that patients treated with GLP-1RAs had a significantly lower risk of incident HCC compared to those receiving other antidiabetic medications, such as insulin and sulfonylureas (Sha et al., 2024)

The interplay of obesity, gut microbiome and diet in the immune check point inhibitors therapy era

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Accompanied by impaired BBB integrity, these peripheral immune factors gain access to the CNS, where they mediate neuroinflammatory responses, resulting in synaptic damage and neuronal dysfunction

doi: 10.1006/bbrc.1993.1246 35 ZhuangJCWoganGN