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Telomerase Is Not a Universal Rejuvenation Switch Telomerase can support continued cell division, but the effect depends on cell type, genomic integrity and tumour-suppressor systems

The most common side effects reported in clinical trials are gastrointestinal issues such as nausea, vomiting, and diarrhea

However, most of these products are illegal for use because their safety and effectiveness are poorly researched

Common side effects include: Nausea Vomiting Diarrhea Decreased appetite Headache Stomach pain Fatigue Constipation Dizziness Heartburn Bloating and gas Low blood sugar (especially with insulin or sulfonylureas) Mood changes Serious, but rare side effects may include: Severe allergic reactions Pancreatitis Gallstones Kidney problems Worsening diabetic retinopathy Heart rate changes Suicidal thoughts or behaviors Thyroid cancer Bowel obstruction This is not a complete list

grades of inflammation were graded from focal to diffuse according to lamina propria infiltration or subendothelial infiltration