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Although a prior cohort study did not show a statistically significant reduction in major cardiovascular events among patients with no previous history of cardiovascular disease [148], a meta-analysis of eight clinical trials evaluating the effect of GLP-1R agonists on cardiovascular outcomes reported a 14% reduction in major adverse cardiovascular events, with no significant heterogeneity across GLP-1R agonists or subgroups, including patients with or without previous cardiovascular disease [149]
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Both of these medications contain semaglutide GLP-1, a powerful aid in weight loss that works by mimicking the hormone glucagon-like peptide-1 (GLP-1), which helps regulate appetite and food intake
The rapid calorie absorption has an addictive effect, she said
