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There have been concerns about thisespecially in the European literature on depression. As is common with most prescription drugs, there can be negative side effects that if left untreated can cause serious harm

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and protects auditory neurons from oxidative damage induced by H2O2 attack (Xie et al., 2004).EGCG acts through phosphatidylinositol 3-kinase (PI3K)/Akt signalling in cochlear NSCs to promote cell growth and neuronal differentiation, which can be used for the treatment of hearing loss (Zhang et al., 2016), and has an important protective mechanism against cochlear oxidative damage