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Although the SAVOR and EXAMINE studies were delineated to verify cardiovascular safety of two DPP-4i, namely saxagliptin and alogliptin, respectively, both are considered to be the first controlled clinical trials to address the effect of GLP-1 system on CVD

rule out both benign conditions (eg, PIH) as well as malignancy (eg, superficial forms of melanoma)

Also, its unclear whether dual receptor activation will outperform standard GLP-1 agents in treating addiction

For example, some doctors recommend eating more whole and high-fiber foods when taking GLP-1 agonists

Some peptides have become increasingly popular amongst professional and amateur athletes, bodybuilders and gymgoers, without strong evidence of advantages or even safety