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Mind meets metabolism Scientists hypothesis that GLP-1 drugs have a role to play in mental health is in part fueled by decades of research that shows that metabolic health and mental health are closely intertwined

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The dual effect is counterintuitive: Less acetaldehyde (liver-protective less toxic metabolite produced) Higher blood alcohol concentration (risky same drinks leave you more intoxicated) As principal investigator Wajahat Mehal, MD, professor of medicine at Yale, stated: "If these results are reproduced in humans, people using GLP-1 receptor agonists might be drinking an amount of alcohol that does not normally put them above the legal blood alcohol level, but because they are taking this drug, it does." Important caveat: This study was conducted in mice