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Glutathione is synthesized in the cytosol of each cell by the action of two enzymes in an elegantly regulated system that allows it to be maintained at different homeostatic levels in different tissue types, with the liver, given its detoxification role, having the highest amounts
Genetic Predisposition and Personalized Glutathione Response Individual glutathione synthesis and metabolism are influenced by genetic polymorphisms in genes encoding glutathione-S-transferase (GST), glutathione peroxidase (GPx), and cysteine metabolism enzymes
Some people are simply more sensitive to these hormonal shifts than others
The tradeoff is speed: cortisone gives faster symptom relief
Not enough
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