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The temporal association between starting tirzepatide and experiencing hot flashes does not necessarily indicate causation

Repeating injections in the same spot can cause constant irritation in the fatty layer

This approach may include the use of calcium channel blockers like nifedipine (Procardia) and alpha-blockers like tamsulosin (Flomax) for four to six weeks (Antonelli 2015)

Defy's advantage is that it operates as a full medical practice with both telehealth and physical clinic options, which gives it more clinical flexibility than an app-first competitor

The OASIS 4 trial showed 13.6% mean weight loss (16.6% with full adherence) at 64 weeks for oral semaglutide 25 mg