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Increases cellular NAD and SAM availability and lowers intracellular 1-MNA, consistent with enhanced NAD salvage and a favorable methyl economy [13]

Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model

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What's missing: No human pharmacokinetic data No human safety data No optimal dose for humans (mouse 20mg/kg = ~150mg in a 75kg human if dose-equivalent, but mouse-to-human scaling for small molecules is unreliable) No drug interaction data No long-term safety data Buyers in this category are doing biohacker-tier self-experimentation with limited data