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Lesser-known genes like COMT (pleasure processing) and DRD2 (dopamine and reward) can heighten cravings, while 5-HTTLPR (serotonin and stress response) and ADRA2B (adrenaline and emotional regulation) increase susceptibility to emotional eating

However, despite these advances, conventional breeding, marker-assisted selection (MAS), and genomic selection continue to play indispensable roles in horticultural crop improvement, particularly for complex polygenic traits and the utilization of naturally available genetic diversity

With regards to evidence related to the effectiveness at stimulating weight loss, the PEN System states, in general, nutraceuticals [(food products (e.g