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Thats because Saxenda has a shorter half-life of 13 hours versus a half-life of around one week with Wegovy
This way any adverse interactions can be avoided
It mainly mediates the inhibitory effect of PYY (1-36) on insulin secretion and the vasoconstrictive effect ( Figure 1 Y2 receptors are primarily expressed in the CNS, including the arcuate nucleus of the hypothalamus, the solitary tract nucleus, and posterior regions of the brainstem, enteric neurons, and peripheral nerve endings (56)
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