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10.4238/gmr.15028787 50 JiangN.LiZ.LuoY.JiangL.ZhangG.YangQ.et al (2021)

A candidate for a potential glutathione-scaffold residue was identified using the following selection criteria: The residue should be rather conserved in enzymatically active in contrast to inactive glutaredoxins and have a charged side chain to ensure a strong ionic glutathione interaction (Fig

S2CID 16400885

While a recent study demonstrated a lack of correlation between GSH levels in the putamen and body status in patients with PD, whole blood GSH was shown to be sensitive to aging with concentrations being correlated to severity of PD progression (Mischley et al., 2016)

So let's break it down: What Does Glutathione Reduced Mean