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This article came out of the Hospital for Special Surgery Journal

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Structural and functional characterization of GS from bacteria demonstrates that this enzyme functions as a tetramer (Yamaguchi et al., 1993), whereas the mammalian, yeast, and plant GS are active as dimers (Polekhina et al., 1999

Therefore, protecting resveratrol from degradation and metabolism, as well as enhancing its delivery into the brain at a therapeutically effective concentration, remains an issue that needs to be addressed for optimizing its therapy

Preliminary clinical evidence supports this hypothesisstudies in obese individuals treated with tirzepatide have shown a downward trend in the apneahypopnea index (AHI), suggesting that tirzepatide may have a beneficial effect on sleep-disordered breathing (28)