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Surgery Some health conditions that cause leg pain may ultimately require surgery, including the following: Achilles tendinitis or torn tendon Bone fracture Neuropathy caused by physical pressure Sacroiliitis Arthritis of the knee Alternative and Complementary Therapies Certain dietary supplements may be beneficial in managing leg cramps or neuropathy

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Its targeted action makes it one of the most commonly used peptides in this category

32,33 Acetyl-L-carnitine in chemotherapy induced neuropathy Clinical studies tested the neuroprotective effect of ALC in chemotherapy-induced neuropathy but no data about neuropathic pain reduction are available

Researchers have discovered that when this peptide is isolated and administered in higher concentrations, its benefits extend far beyond the digestive system (Seiwerth et al., 2014)