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Management of Hyperglycemia in Type 2 Diabetes, 2022
Sci Rep 14(1):14669
Patients with normal or high-normal IGF-1 levels for their age group may not be appropriate candidates, as further GH stimulation in these individuals carries a different risk-benefit profile than in patients with documented decline
This difference became even more pronounced when comparing TCC-treated wounds to control wounds on days 7, 14, and 21, where the TCC group consistently showed significantly smaller unhealed areas
, while IL-1 or TNF blockers might reduce sterile inflammation, they could predispose to infection in the immune-compromised postoperative host
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