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Summary of Current and Ongoing Research The exploration of GLP-1 receptor agonists in mental health is an exciting and rapidly evolving field
Modelling suggests a return to baseline weight in ~1.7 years with GLP-1s, compared with ~3.9 years after behavioural weight management
One was studied in controlled trials with defined adverse-event reporting
Similar to irisin, sFNDC5 possessed lipolysis action on cells and adipocytes and executed anti-obesity effects in the mouse model
GLP-1RA also causes apoptosis of CD3 + T cells (Ben et al., 2024), contrary to NK stimulation
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