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ES NDs effectively reduce the abnormal accumulation of Fe 2+ , GPX4 inactivation, and lipid peroxidation in chondrocytes, thereby improving the metabolic disorders of chondrocytes caused by ferroptosis, and show significant therapeutic effects in alleviating OA
G-1, No
We further hypothesized that short-term dietary supplementation of two key amino acid precursors of GSH, glycine and cysteine, would increase intracellular GSH synthesis and concentrations and thus lower oxidative stress, despite continuing hyperglycemia
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These foods include avocado, asparagus, and spinach
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