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doi: 10.1038/nri.2017.21 138 WestmanJ.WalpoleG

Plain or lightly prepared coffee is a better choice than drinks loaded with sugar, flavored syrup and cream

Early lab and animal studies suggest improved absorption and cellular uptake compared to standard ALA.58 However, human studies are limited, so its clinical superiority remains unproven

Several papers describe upregulation of the vascular endothelial growth factor receptor 2 ( VEGFR2 ) pathway and downstream nitric oxide signalling the so-called VEGFR2-Akt-eNOS axis which researchers hypothesise underlies its reported influence on wound healing and blood-flow restoration at an injury site