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Most users find nausea manageable after day 5

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Together, these findings and the present analysis underscore that weight change alone does not fully explain the CV effects of GLP-1RAs and highlight the need for further research into mechanisms of GLP-1RA-induced cardioprotection beyond weight loss

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Further, 6 weeks of HFD has been shown to decrease reduced glutathione (GSH) levels, an important antioxidant, in the gastrocnemius of 8-week-old SpragueDawley rats (Anderson et al., 2009)