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Yamada et al., 2020), which is not supported by the data obtained under pathophysiologically relevant condition (Wang et al., 2021

Concurrent iron-deficiency anemia and folic acid deficiency may result in a blunted or impeded response to cyanocobalamin therapy.1

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Mechanism of Action: How Does 5-Amino-1MQ Work NNMT transfers a methyl group from S-adenosyl methionine to nicotinamide, producing 1-methylnicotinamide