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J Orthopaed Surg Res (2021) 16(1):116
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Using fatty acids to prolong the duration of the action of peptides and proteins was already a long established technique at Novo Nordisk and elsewhere and had been successfully applied to insulin (insulin detemir) (Knudsen, Lau)
(126) observed that GLP-1R signaling exerted more robust control of -cell survival, relative to GIPR activation
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