In mouse studies, NNMT inhibition reduced white adipose tissue mass by approximately 35% without any change in food intake
According to research, it appears they do this in two ways: by scavenging free radicals before glutathione has to and by assisting in glutathione regeneration
Daniel Drucker's research at the Lunenfeld-Tanenbaum Research Institute at Sinai Health in Toronto helped pave the way for GLP-1 medications
[8] Early small-scale research suggested it may stimulate lipolysis (the breakdown of fat) and inhibit lipogenesis (fat storage), with preliminary data indicating it may not significantly affect blood glucose or insulin-like growth factor-1 (IGF-1) levels
Fang X, Wang H, Han D, Xie E, Yang X, Wei J, Gu S, Gao F, Zhu N, Yin X, et al